I think it is clear to me that the Garden of Eden was conceived of as being located in some mystical location at the eastern end of the earth. This description fits well with the notion that Eden is located ‘in the east’, and is where the tree of life, which grants immortality grows, consistent with Mesopotamian descriptions of Dilmun.
But my main reason for holding this view is that this is indeed how early Jewish and Christian works such as 1 Enoch, the Apocalypse of Ezra and the Alexander Romances understood it.
Add to this the Syriac tradition that the Garden of Eden was some sort of cosmic mountain stretching into the heavens, and I think a picture is emerging, namely that the Garden was seen of as being located in some sort of mystical location, which cannot be reconciled with real world geography.
And it makes a beautiful story, let’s not try to rationalise it away.