Bradykinin storm in Covid 19

Michelle, I am hearing this from front line doctors and want to save lives of somesones grandparent or someone’s child. I have detailed this about the Dexamethasone in previous posts. As mentioned we all thought this was ARDS and that was just not correct. However the lancet article was written by researchers that had not even seen a Covid patient. As mentioned articles coming out from China suggested Dexamethasone was beneficial and in fact I am hearing from doctors that they are seeing benefit now with even longer term steroid treatments than was done in the study to the slow responders. When the U.K. recovery study came out many US doctors were literally blindsided not understanding how they could have been told guidelines not to use steroids at the same time there were some US doctors amazed at all this as they were using steroids successfully all along with lower mortality rates. The lesson here is that we didn’t know and understand what this disease is and we shouldn’t tie the hands of doctors particularly with unproven restrictions.

June 2020 The systematic failure of critical care systems to adopt corticosteroid therapy resulted from the published recommendations against corticosteroids use by the World Health Organization
(WHO) [151,152]. This recommendation was then perpetuated by the Centers for Disease Control and Prevention (CDC), the American Thoracic Society (ATS), Infectious Diseases Association of America (IDSA) amongst others. A very recent publication by the Society of Critical Care Medicine and authored one of the members of the Front Line COVID-19 Critical Care (FLCCC) group (UM), identified the errors made by these organizations in their analyses of corticosteroid studies based on the findings of the SARS and H1N1 pandemics.[55,153] Their erroneous recommendation to avoid corticosteroids in the treatment of COVID-19 has led to the development of myriad organ failures which have overwhelmed critical care systems across the world and led to excess deaths. The recently announced results of the RECOVERY- DEXAMETHASONE study provides definitive and unambiguous evidence of the lifesaving benefits of corticosteroids and strong validation of the MATH + protocol. The RECOVERY-DEXAMETHASONE study, randomized 2104 patients to receive dexamethasone 6 mg (equivalent to 32 mg methylprednisolone) once per day (either by mouth or by intravenous injection) for ten days and were compared with 4321 patients randomized to usual care alone. Dexamethasone reduced deaths by one-third in ventilated

You are speaking to doctors at which institutions/hospitals, with what type of experience? how many doctors told you these things? when were your conversations with them? Are they still struggling to use corticosteroids and vitamin D with patients when needed now that more information is widely available? We need more specifics to understand your criticisms
What would stop them from using vitamin D?

where did you quote that last paragraph on corticosteroids? Looks like its pulled from an article, because it has citations in it.

I’d also be interested to hear more about your background, how you know so many doctors and why they are airing their frustrations with you.


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