Are there problems with the evolutionary scenario?

You’re making this up. Who has ever studied those alleles? Do we even know how many alleles there are?

Again, you’re making up the “required” time. You simply have no idea what it takes to get from E. Coli to amoebae.

These unrelated topics don’t help your argument …aside from the fact that Big Bang is itself a questionable model which I will not discuss here.

I am not sure you even understand my position. If you care, you might want to start here: http://nonlin.org/evolution/