Okay, fine. I’m not going to make a mountain out of it.
I’ll just mention that as a diagnostic, when I see someone has posted a text in response to most every separate sentence, or every other sentence, where some comments are purely rhetorical, I don’t get “warm vibes”. And I don’t think I’m unique in this regard.
There are a few posters who are rather famous here for the “machine gun belt” commentary method:
So, if I promise to never bring it up to you again, can we move along to the actual question part of my last post?
So, let’s try to push the envelope a little further. Have you folks come up with a relatively good estimate of how many sites on the 23 human chromosomes are active, and thus can serve as a de facto denominator for this mutation rate of 50 to 100?
I am guessing that an inactive site could mutate and suddenly become active… but for the purposes of a ratio, I think just using “average total active sites” for your typical human can provide the necessary benchmark for discussing average total pace of mutations.