Liam, I would essentially answer this by going back to these analogies. We don’t blink an eye at the idea that an archaeologist makes his living by testing and distinguishing marks on rocks, or examining artifacts, and making distinctions between, say scratches on rocks that are entirely “natural”, and those that were caused by intelligent intervention. And no one would fault him for so doing.
Similarly, a SETI scientist’s entire enterprise is predicated on the idea that they can, scientifically, distinguish between background noise, or signals of natural cause or origin, and radio signals which exhibit signs of intelligent agency.
We could also consider forensics, where scientists try to discriminate between deaths that were by “natural causes” and those that we caused by intelligent agents on purpose.
These particular scientists could undoubtedly test for intelligent intervention, and no one would seriously call them unscientific for so doing. And of course, if any of these had legitimate reasons for concluding intelligent agency in their respective fields, no one would claim they were making a “intelligent agent of the gaps” argument.
In principle, logically, one should be able to examine a biological system just as well as a rock, radio signal, or corpse, and use the very same basic principles to make a judgment about natural causes vs. intelligent purpose. Indeed, if science progresses at it seems to do, and we begin to genetically modify organisms with more and more creativity and skill, there may well be in the future an entire field of science devoted to determining if certain biological features were indeed “man-designed”, or “naturally-occuring”.
In other words: a geologist could explore Stonehenge, and then examine Giant’s Causeway, and use his various skills and methods to determine that one was purposed by intelligent agents, the other naturally occurring. Why can this essentially identical investigative method not be used for a biological system?