Does it?
In the case of antibiotic resistance for instance the resistance is often due to a defect that disables the pathway used by the antibiotic, But there is only so far you can go by breaking things; that’s devolution. Similarly this has been observed in Lenski’s LTEE. Rather than evolution creating new things we see it breaking or deleting existing genetic information. This is the wrong way for Darwinism but compatible with Creationism.