It sounds from that as if, to you, “knowledge of reality” means “science”. This is the knowledge that appears to require (potentially) changes to a lesser form of knowledge, our "theological structure, "hitherto based on uncertain principles. I’m not sure how that differs from what some have termed “soft scientism” (the belief that science is the source of knowledge by which all others must be judged), but leaving that terminology aside I’ll make just one point.
If theology is defined as “the study of the nature of God and religious belief”, then the claim appears to be that scientific knowledge (derived from the patterns discernible in material processes) is (a) unambiguous and (b) has the ability and authority to modify our understanding of “God and religious belief.”
Now, The Intelligent Design crowd are condemned widely for suggesting that science can lead to an understanding of whether there are signs of mere design in nature, without commenting on any theological implications of that. That claim would appear to be orders of magnitude more modest than what you’re suggesting.
I propose a different, more modet model: (a) physical reality contains physical truth (because God is truthful). (b) Divine revelation contains truth about God and religion (because God is truthful). Science and theology are fallible human pursuits that seek to elicit those truths and, perhaps, integrate them as do other valid and necessary human endeavours like philosophy, contemplation and worship.
It is the fact that all these, and the usual human weaknesses, interact with each other that makes knowledge messy and incomplete. To privilege one source above the others is usually due to a failure to recognise the humanness of gaining knowledge.