Evolution is a faith because common ancestry doesn't add up

Current estimates for the human mutation rate range roughly from 1.0 to 1.7 x 10^-8 mutations per bp per generation. Note that these estimates are almost always for the single-base substitution rate; the total mutation rate, including insertions and deletions, will be something like 20% higher. That translates into 30 to 50 single-base substitutions per genome copy per generation. If human-chimpanzee speciation occurred 7 million years ago, from an ancestral population size of 50,000, and if mean generation time was 25 years, then a human and a chimpanzee genome should be separated by ~380,000 generations (280,000 generations back to the speciation time, and another 100,000 generations for chromosomes within the ancestral population to coalesce). With the range of mutation rate estimates from above, that means we should expect to see between 23 million and 39 million single-base substitutions when comparing human and chimpanzee genomes. We actually observe 35 million. Where’s the problem, exactly?

No, there need be no bottleneck in speciation.

I don’t know what you’re trying to say here, but it doesn’t seem to have anything to do with the calculation you’re trying to do. Population size is irrelevant if you’re calculating the difference between two genomes – you’re just counting how many mutations have occurred in the two lineages since the two copies were identical.

I know of no evidence that this is true. If anything, modern chemical exposure might have increased the mutation rate, not decreased it.

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