[quote=āBillcole, post:129, topic:5974ā]
Hi Ben
This is fundamental to our disagreement is contrary to the vast biochemical evidence.[/quote]
Really? Yet you havenāt offered a speck of evidence to support your claim!!!
What have you observed, Bill? Iām still waiting for you to support your claim about the evidence:
So, show me the data. I took a break from revising the paper weāve submitted to the Journal of Biological Chemistry (loaded with binding assays, btw) and I canāt find anything to support your claim.
Itās relative affinity that matters, Bill. Thereās no real black/white. Itās the sort of complexity we expect from evolution.
First, not all are in binding sites. Second, the ones that are change relative affinities, not off/on. And itās āimplicated,ā not āimplied.ā
Itās virtually all relative, not absolute.
[quote]Ask yourself honestly, are you making this claim because without it stochastic evolution is highly unlikely?
[/quote]Iām making my claim because it reflects reality.
Honestly, Bill, why are you making direct claims about the evidence, then trying to shift the burden of support when challenged?
Do you realize that you have inadvertently tested a hypothesis about how biochemistry should work if it were intelligently designed?
Please show me the binding assays that support your claim, Bill.